Variational Inference for Markov Jump Processes Manfred Opper T.U. Berlin Guido Sanguinetti University of Sheffield Markov Jump Processes (MJP): stochastic processes for integervalued random variables in continuous time. They are common in many applications: single cell biology, ecological models, telecommunications, etc. They are widely studied through simulation (Gillespie's algorithm); inference however is a long standing problem. We propose a novel meanfield algorithm that allows practical inference. We demonstrate the method on two examples, the classic LotkaVolterra predatorprey model and a gene autoregulatory network.